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Epigenetic Modifications and Their Role in Cancer: DNA Methylation and Histone Modifications
Editor: Yonghwan Shin

Submission Deadline: 31 March 2025 (Status: Open)


Special Issue Editor(s)


Dr. Yonghwan Shin      Email 1   |   Email 2   |   Website
Department of Biochemistry and Molecular Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
Interests: epigenetics; DNA methylation; histone modifications; cancer; bone; salivary gland; zebrafish


Special Issue Information

Dear Colleagues,

Epigenetics—the study of heritable changes in gene expression that do not involve alterations to the DNA sequence—is crucial to the understanding cancer biology. This special issue delves into the pivotal mechanisms of DNA methylation, including hypermethylation and hypomethylation, and their impacts on gene regulation and cancer development. Additionally, various types of histone modifications, such as histone methylation and histone acetylation, which significantly influence chromatin structure and gene expression, are also topics of interest. This special issue aims to provide comprehensive insights into the roles of epigenetic modifications in oncogenesis and tumor progression. Of additional interest to this special issue is the potential applicability of epigenetic markers as diagnostic tools and therapeutic targets for cancers. Furthermore, papers involving recent advancements in epigenetic research and their implications for personalized medicine are also welcomed. Addressing multiple facets of this theme, this special issue will serve as a vital reference for researchers and clinicians striving to understand the epigenetic landscape of carcinogenesis and cancer progression, as well as to develop innovative approaches to diagnosing, treating, and preventing various cancers.

Dr. Yonghwan Shin
Guest Editor


Keywords

epigenetics; DNA methylation; hypermethylation; hypomethylation; histone modifications; histone methylation; histone acetylation; cancer


Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.discovmed.com/Journalx_dm/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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